NOVIRUSES2BRAIN Activities

Brain Awareness Week 2022

As part of the Brain Awareness week, Miguel Castanho Lab was at Quinta da Vala primary school Vila Franca de Xira on March 17, 2022 to talk about “Developing smart drugs to treat the brain”. Around 64 students from the 3rd-grade learned about the blood-brain barrier, looking at cells under microscope and by simulating a small experiment. We have received …
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Models of the Blood-Brain Barrier (BBB)

Models of the BBB was an online event with the following theme: “Scientific tools to target the brain”, organised by the Faculty of Pharmacy, University of Lisbon (March 18-20, 2022). NOVIRUSES2BRAIN researchers, Miguel Castanho and Vera Neves from faculty of Medicine, University of Lisbon gave two scientific talks about “Drug conjugation as a tool to overcome the BBB” and “Peptides shuttles for receptor-independent transport across the BBB”, respectively.

Research Exchange between Brazil and Europe

PhD Student, Daniel Gavino, from the Federal University of Rio de Janeiro (Brazil) has visited the Miguel Castanho Lab at Instituto de Medicina Molecular João Lobo Antunes (Lisboa, Portugal) to share his expertise in the animal model of Zika viral infection and to learn more about other biophysical techniques.   

4th Periodic Working Meeting

On December 10th, the NOVIRUSES2BRAIN consortium met for the 4th Periodic Working Meeting. The team evaluated the drug leads that fit the “One size fits all” goal and is now starting the next step of the project.  

World Environment Day 2021

On World Environment Day (5th June), citizens of the Santa Casa da Misericórdia Fátima-Ourém had a different day with the virtual visit of the scientist Vera Neves and heard about biomedical research, understanding how to study the brain and how drugs can help in neurodiseases. 

HIV. Portuguese create molecules that help treat neurocognitive disorders

Professor Miguel Castanho, principal investigator at Instituto de Medicina Molecular João Lobo Antunes (Lisboa, Portugal), explains how these molecules can help when the virus settles in the brain (December 13, 2021). https://observador.pt/programas/e-mc2/vih-portugueses-criam-moleculas-que-ajudam-a-tratar-disturbios-neurocognitivos/ (in portuguese).

More resistant viruses: Blame the antibiotics

“Did you know that antibiotics are used in cleaning and food? Excessive use makes viruses resistant to treatments”, explains Professor Miguel Castanho, principal investigator at Instituto de Medicina Molecular João Lobo Antunes (Lisboa, Portugal), during the E=mc² program on Observador Radio (November 30, 2021). https://observador.pt/programas/e-mc2/virus-mais-resistentes-a-culpa-e-dos-antibioticos/ (in Portuguese)

World Brain Day 2021

Professor Miguel Castanho, principal investigator at Instituto de Medicina Molecular João Lobo Antunes (Lisboa, Portugal), joined the round table to discuss the new Technologies and Innovation Challenges in Neurosciences (July 22, 2021).

7th International Iberian Biophysics Congress

Two members of NOVIRUSES2BRAIN project attended to the 7th International Iberian Biophysics Congress which took place on 14-16 June 2021 in an online format. Professor Miguel Castanho gave a lecture on “Pursuing innovative peptide drugs with biophysical approaches: why, what, what for?” and the PhD student Diogo Mendonça gave a scientific talk on “Novel peptide-porphyrin conjugates efficiently translocate a cellular model of the blood-brain barrier and inactive ZIKV in vitro.”

3rd Periodic Working Meeting

The 3rd Periodic Working Meeting included all the team members and took place by videoconference. The project has now a set of preliminary and promising results regarding the study of molecules efficacious against Zika, Dengue, HIV and SARS-CoV-2 viruses.